[blindkid] {Disarmed} Article: Successful treatment for lessening effects of autism-spectrum ..

H. Field missheather at comcast.net
Wed Mar 2 02:22:32 UTC 2011


I'd like to know as well. :) I guess you can do some research and let 
the rest of us know. I just forwarded from another list and know 
nothing more than the article says.

Best,

Heather
----- Original Message ----- 
From: "Marshall Flax" <marshall.flax+blindkid at gmail.com>
To: "NFBnet Blind Kid Mailing List,(for parents of blind children)" 
<blindkid at nfbnet.org>
Sent: Tuesday, March 01, 2011 8:04 PM
Subject: Re: [blindkid] {Disarmed} Article: Successful treatment for 
lessening effects of autism-spectrum ..


Any peer-reviewed double-blind studies?

Thanks!

Marshall

On Tue, Mar 1, 2011 at 8:50 PM, H. Field <missheather at comcast.net> 
wrote:
> FYI:
> Respen-A and Autism - An Important Treatment To Consider For Anyone
> On The Autism-Spectrum
>
> by Kurt Woeller
>
> An exciting new therapy called Respen-A is showing great benefit for
> individuals on the autism spectrum with respects to some of their
> core issue such as language delay, socialization, self-stimulatory
> behavior and cognitive dysfunction. Respen-A has been available 
> since
> 2008, but not until recently has increased interest been recognized
> within the autism community of its benefits. So what is Respen-A and
> what does it do?
>
> Respen-A is a small disc (about the size of a nickel) applied to the
> skin once daily for 12 hours. In the disc is an ingredient called
> reserpine in a small dose that helps to activate a particular enzyme
> in the human bo dy called Monoamine Oxidase A (MAO-A). MAO-A helps
> metabolize three primary neurotransmitters called histamine,
> serotonin and norepinephrine. In autism, serotonin is greatly
> affected which results in issues such as poor mood regulation,
> tantrums, and anxiety. Also, fine and gross motor skills,
> self-regulation problems, and sensory system imbalances such as
> touch, sound, etc. are prevalent too.
>
> Reserpine is a known as a MAO-A agonist which means it promotes 
> MAO-A
> activity, and in doing so helps to turn serotonin over into what's
> called its active aldehyde form. This aldehyde form called
> 5-hydroxyindoleacetaldehyde (5-HIAL) complexes with the 
> post-synaptic
> serotonin receptor to influence the physiological effects of 
> serotonin.
>
> Reserpine comes from an Indian herb called Rauwolfia serpentina or
> snakeroot. In 1955, the FDA approved reserpine for the treatment of
> hypertension at a dose of 0.1- 0.5mg. The actual amount of reserpine
> found in Respen-A is .01 mg, which i s about 10 to 50 times less 
> than
> was used in the other forms of reserpine products.
>
> Respen-A was first introduced in November 2008 as a viable therapy
> for autism-related disorders. The impetus for this therapy came from
> research that was published in 1957 in the Journal of Nervous and
> Mental Disease. A study had been done with reserpine in a group of
> autistic children using an oral elixir dose between 3 - 7 mg (much
> higher than is found in Respen-A). What they discovered in these 
> kids
> was better verbal communication, improved eye contact, much less 
> self
> stimulatory behavior, improved general awareness, willingness to
> play, and willingness to socialize. These are the same types of
> things I am seeing with many autistic children who are doing the
> Respen-A therapy.
>
> There are two main areas that appear to be helped the most with
> Respen-A. These are speech and socialization problems, but it must 
> be
> understood that others area related to autism described above can be
> improved as well. Speech improvements with Respen-A seem to manifest
> as more complex speech, expressive and specific. As some parents 
> have
> described to me, their child's speech has become more purposeful and
> deliberate. Socialization seems to manifest with children becoming
> more aware of others around them (particularly other children), and
> they are more interested in interacting and happier to do so. Mood
> has also been improved with this therapy as well.
>
> Side effects of any therapy are an important part of the discussion
> and Respen-A is no exception. Thankfully, side effects from this
> therapy have been minimal and easy to deal with. In the early use of
> reserpine at high dosages such as the case in the 1957 study some
> children experienced excessive sleepiness, dry mouth, and fatigue
> (possibly from lower blood pressure). When the dosage was pushed
> upwards of 10 aa??" 12 mg some kids started to take on adverse
> neurological complications similar to Parkinson's with impai red
> gait, slowed physical movements and tremors. With Respen-A the main
> side effect is initial hyperactivity in a small number of children
> which is easily remedied by decreasing the size of the patch
> application. Also, calcium supplementation is necessary with 
> Respen-A
> to help prevent against irritability which can happen as reserpine
> has a tendency to drop blood calcium levels a bit. Finally,
> individuals on Respen-A need to eat some protein every day, i.e.
> fish, chicken, beef, turkey, or take an amino acid supplement such 
> as
> 5-HTP to help replenish lost stores of serotonin via MAO-A activity.
> Overall, the side effects of Respen-A are minimal and easily
> accounted for with these additional steps.
>
> Respen-A therapy has been very helpful for individuals on the
> autism-spectrum, and in my experience has shown a positive response
> rate of 75-80% and greater. These are exceptional numbers and I
> consider it to be one of the higher ranking therapies used in
> treating many of the core issues in autism. For more information
> about Respen-a please visit 
> (<http://www.respen-a.com/>www.respen-a.com).
>
> http://www.naturalnews.com/031525_Respen-A_autism.html
> I hope this helps. I do not sell anything nor am I involved in any
> kind of diagnosis, treatment of anything ... I post this only for
> informational purposes.
>
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