[Diabetes-talk] Emailing: Misinformed Immune System May Cause Type I Diabetes - Diabetes Health.htm

catdancing catdancing at sbcglobal.net
Fri Sep 4 20:33:32 UTC 2009 

Misinformed Immune System May Cause Type I Diabetes - Diabetes Health
      My Account   |  Subscribe  |  Contact Us  |  Donate  

             Search  
 Home News & Blog Forums Digital Edition TV Community 

  a.. Type 2 Issues 
  b.. Type 1 Issues 
  c.. Kids & Teens 
  d.. Professional Issues 
  e.. Beginners 
  f.. Events 
  g.. History 
  h.. Camps for Kids 
  i.. Online Resources 
  j.. Dating 
  k.. International 
  l.. Pre-Diabetes 
  m.. Health 
  n.. Pets 
  o.. Scholarships 
  p.. All Sections

Products 

  a.. Product Directory 
  b.. Charts 
  c.. Syringes 
  d.. Insulin Pumps 
  e.. Meters 
  f.. Pens 
  g.. Software 
  h.. CGMs 
  i.. Medical ID Jewelry 
  j.. Lancing Devices 
  k.. Carrying Cases 
  l.. Infusion Sets 
  m.. Pen Needles 
  n.. Books 
  o.. All Sections

Complications & Care 

  a.. Heart Care & Heart Disease 
  b.. Low Blood Sugar 
  c.. Foot Care 
  d.. Kidney Care (Nephropathy) 
  e.. Sexual Issues 
  f.. Nerve Care (Neuropathy) 
  g.. Eye Care (Retinopathy) 
  h.. Lipid Problems 
  i.. Hypoglycemia Unawareness 
  j.. Depression 
  k.. Skin Care 
  l.. Oral Health 
  m.. Celiac Disease 
  n.. Wound Care 
  o.. Gastroparesis (Digestion Problems) 
  p.. All Sections

Food 

  a.. Recipes 
  b.. Diets 
  c.. Vitamins 
  d.. Food News 
  e.. Nutrition Advice 
  f.. Low Carb 
  g.. Glycemic Index & Carb Counting 
  h.. Supplements 
  i.. Low Calorie & Low Fat 
  j.. Beverages 
  k.. Desserts 
  l.. Herbs 
  m.. Dinner 
  n.. Lunch 
  o.. Fast Food 
  p.. All Sections

Columns 

  a.. Cartoons & eCards 
  b.. Personal Stories 
  c.. Letters to the Editor 
  d.. My Own Injection 
  e.. Inspiration 
  f.. Book Reviews 
  g.. Heroes 
  h.. CDE of the Month 
  i.. Making a Difference 
  j.. Doctors & Nurses 
  k.. Motivation 
  l.. After All These Years 
  m.. Love and Diabetes 
  n.. All Sections

Fitness 

  a.. Exercise 
  b.. Weight Loss 
  c.. Bariatric Surgery 
  d.. Success Stories 
  e.. Amphetamines 
  f.. All Sections

Medications 

  a.. Insulin 
  b.. Type 2 Medications 
  c.. Metformin 
  d.. Pharmacy 
  e.. Byetta 
  f.. Lantus 
  g.. Animal Insulin 
  h.. Januvia 
  i.. Symlin 
  j.. Actos 
  k.. Victoza 
  l.. Onglyza 
  m.. Insulin Rescue Therapy 
  n.. Apidra 
  o.. Voglibose 
  p.. All Sections

Research 

  a.. Nutrition Research 
  b.. Islet & Pancreas Transplant 
  c.. Medications Research 
  d.. Other Lab Tests 
  e.. Artificial Pancreas 
  f.. The Cure 
  g.. Health Research 
  h.. New Cure Research 
  i.. Case Studies 
  j.. Beta Cells 
  k.. All Sections

Monitoring 

  a.. Blood Sugar 
  b.. A1c Test 
  c.. Noninvasive Monitors 
  d.. Urine Test 
  e.. Laboratory Tests 
  f.. All Sections

Health Care 

  a.. Health Insurance 
  b.. Hospital Care 
  c.. Complementary Therapies 
  d.. Endocrinology 
  e.. smoking 
  f.. Physical Therapy 
  g.. All Sections

Psychology 

  a.. Support Groups 
  b.. Living with Diabetes 
  c.. Adolescent Boys 
  d.. Adolescent Girls 
  e.. Teenagers 
  f.. Women's Issues 
  g.. Men's Issues 
  h.. Insulin Omission 
  i.. All Sections

Legal 

  a.. Discrimination 
  b.. Government & Policy 
  c.. Politics 
  d.. Drivers License & Pilot License 
  e.. Driving 
  f.. Lobbying 
  g.. 504 Plan in School 
  h.. All Sections

Celebrities 

  a.. Nick Jonas 
  b.. Jay Hewitt 
  c.. Scott Dunton 
  d.. Elliott Yamin 
  e.. All Sections

Pregnancy 

  a.. Breastfeeding 
  b.. Childbirth 
  c.. Gestational Diabetes 
  d.. All Sections

About Us

  a.. About Us 
  b.. Publisher's Letter 
  c.. Advertising 
  d.. Contact Us 
  e.. Press Room 
  f.. Submission Guidelines 
  g.. Privacy Policy 
  h.. Help 

ADVERTISEMENTADVERTISEMENT 


 
 
See What's Inside…
  a.. A Chat with Kelli Kuehne on Life, Golf, and Diabetes 
  Golfer Kelli Kuehne won the United States Girls Junior Amateur Golf Championship and has twice won the U.S. Women’s Amateur Golf Championship. She’s never allowed type 1 to beat her on the golf course or in her life.

  b.. An Insulin Primer 
  Learn important facts about insulin—it’s history and what the terminology means. You can also learn other stuff.

  c.. Hypoglycemia! A Grateful Nod to What Parents Go Through 
  Curtis Charling realized in his 20’s that he was ultimately responsible for his own actions—especially when it came to diabetes, it was one of the biggest lessons he received from his parents.

  d.. Diabetes and the iPhone 
  People with diabetes can prosper from iPhone diabetes applications and there’s a lot to look forward to in the future.

  e.. Managing Type 2 Abroad 
  Jo & Simon Lamb packed up their life in the UK and moved to Italy. This was a huge undertaking and managing Simon’s diabetes made it more complicated. Jo shares some of the issues they experienced and the lessons they learned while traveling with diabetes.

  f.. Parenting with Diabetes 
  Author Rachel Garlinghouse’s greatest anxiety about parenthood stemmed from the fear of losing control of her diabetes. Find out how she coped and what she learned in her first year of being a mom.

 

View Diabetes Health Magazine For Free Online
You can view the current or previous issues of Diabetes Health online, in their entirety, anytime you want. 
Click Here To View 

Free Subscription to Diabetes Health Professional
If you are a physician, educator and medical professional who focus on the treatment of diabetes, then this is the must have resource for you.

Finally! A fresh take on the “professional” journal. Each bi-monthly issue cuts through the jargon and presents the most important information you need to enhance your practice and assist your patients. 

Each bi-monthly issue of Diabetes Health Professional is a self-contained handbook covering products, educational resources and the latest diabetes research, complimented by balanced editorial focused on medical news, drug prescription information, clinical practice recommendations and changing treatment options.

Each quarter we send you the latest, most updated research guides, product guides and educational resource guides available for you and your patients. 


 
Each week the Diabetes Health E-Newsletter delivers links to the very latest in news, reviews, blogs and videos from Diabetes Health direct to your inbox. 



As a subscriber you'll get access to the amazing Diabetes Health Digital Advantage™ so you can read the current issue of Diabetes Health magazine online wherever you are! 

      Email Address:    
      Area of Interest:   Consumer Professional 
          
         
 
How To Change Your Newsletter Email…
You can cancel your newsletter subscription at anytime by clicking "Unsubscribe" on the bottom of any newsletter you receive

Then enter your new email address in the above form and click "Subscribe"

ADVERTISEMENTLatestPopularTop RatedLatest Type 1 Issues Articles

Misinformed Immune System May Cause Type I Diabetes 
Oil Lowers Body Fat, But Don't Rub It In 
Abnormal Response to Wheat Protein May Provide Clue To Cause of Type 1 Diabetes 
New Video: Diabetes Myths Debunked 
Sticking To It: Potential Drugs for Diabetes-Related Vascular Issues 
Japanese Company's Stock Jumps 10 Percent on News of Insulin Nasal Spray 
To be or not to be... a pancreatic beta cell 
FDA Issues Warning About Test Strips That Can Give False Readings, Lead to Insulin Overdoses 
A New Anti-Ras Drug 
Type 1 Diabetes Appears to Increase the Risk of TB Popular Type 1 Issues Articles

Type 1 Pop Star, Nick Jonas Tells His Story 
Bret Michaels, Diabetic Lead Singer of 
Lantus and Levemir: What's the Difference? 
Low Carbohydrate Diets: Why You Don't Want the "Experts" to Tell You What to Eat 
Scrawny Boy With Type 1 Diabetes Becomes Mr. Universe 
Legal and Illegal Drugs: What Every Person With Diabetes Should Know Before They Party 
Why Eating Too Many Carbs Makes You Fat 
Halle Berry Says She's Worked Her Way Up From Type 1 to Type 2 Diabetes 
Jonas Brothers Band Member Reveals He Has Diabetes: Nick Jonas, age 14, hopes his story will inspire other kids with diabetes 
Jonas Brothers Update: Diabetes Has Not Slowed Down 15-Year-Old Nick Jonas Highly Recommended Type 1 Issues Articles

Type 1 Pop Star, Nick Jonas Tells His Story 
Jonas Brothers Band Member Reveals He Has Diabetes: Nick Jonas, age 14, hopes his story will inspire other kids with diabetes 
Jonas Brothers Update: Diabetes Has Not Slowed Down 15-Year-Old Nick Jonas 
Low Carbohydrate Diets: Why You Don't Want the "Experts" to Tell You What to Eat 
Bret Michaels, Diabetic Lead Singer of 
Has Anyone Else Reversed Diabetes Complications? If You Have, I Want to Hear From You! 
Mr. Universe Assaulted by Police During Low Blood Sugar Episode 
Scrawny Boy With Type 1 Diabetes Becomes Mr. Universe 
Lantus and Levemir: What's the Difference? 
Halle Berry Says She's Worked Her Way Up From Type 1 to Type 2 Diabetes 

Diabetes Health Reference Charts
Continuous Glucose Monitors Reference Guide (PDF) 
Continuous Glucose Monitors Reference Guide (PDF) 
Skin and Foot Care Reference Guide (PDF) 
Mail Order Reference Guide (PDF) 
Blood Pressure and Cholesterol Medications Reference Guide (PDF) 
Insulin Reference Guide (PDF) 
Sugar-Free Foods Reference Guide (PDF) 
Insulin Pens Reference Guide (PDF) 
Medical Nutritionals Reference Guide (PDF) 
Sugar-Free Chocolate Reference Guide (PDF) 
See All Charts… 

Type 1 Issues Archives
Browse the Type 1 Issues Archives 
Subscribe to the Community RSS Feed 

ADVERTISEMENTPrint | Email | Share | Comments (0) 
Email to a Friend
Send a link to this page to your friends and colleagues.

 Your Name: Your Email: 
      
      Recipient's Name: Recipient's Email: 
      
      Close    

 
The identification of this variant gene may help scientists develop a treatment for type 1 diabetes. 
Misinformed Immune System May Cause Type I Diabetes
Sep 3, 2009 
Researchers at Stanford University recently discovered that a deformed version of a gene may contribute to type 1 diabetes by sabotaging the functioning of the gene's normal version. Experiments conducted on mice with a diabetes-type disease showed that the deformed variant may prevent the healthy version from protecting the insulin-producing cells in the pancreas from attack by the immune system.

The gene, called Deaf1 (deformed epidermal autoregulatory factor 1), is a transcriptional regulator, which means that it controls the transfer of information necessary for certain functions to take place. Deaf1 is present in the body in two forms, a longer normal version and a shorter dysfunctional version. The long, normal version of Deaf1 produces molecules that protect cells from attack by the body's immune system. This is particularly relevant to those suffering from type 1 diabetes because the molecules produced by the longer version help protect the insulin-producing cells in the pancreas from that unfortunate fate.

C. Garrison Fathman, M.D., and his team at Stanford showed that a prevalence of the shorter version of Deaf1 actually dissuaded the longer version from producing these protective molecules, thus allowing the insulin-producing cells of the pancreas to be damaged. Applying their findings from the mouse experiment to human subjects, the researchers discovered a correlation between higher levels of the variant Deaf1 gene and people with type1 diabetes.

The identification of this variant gene may provide guidance in the development of a treatment that would interact with the Deaf1 protein and help to treat type 1 diabetes.

The research was funded by a grant from the National Institute of Allergy and Infectious Diseases and the National Institute of Diabetes and Digestive and Kidney Diseases, both components of the National Institutes of Health. Additional funding came from the Special Statutory Funding Program for Type 1 Diabetes Research.         


--------------------------------------------------------------------------------

Categories: Complications, Research, Type 1 Issues


--------------------------------------------------------------------------------

 Facebook  MySpace  Digg  Recommend this : 
Not at all Somewhat Moderately Highly Very Highly 

Average Rating: 



--------------------------------------------------------------------------------

You May Also Be Interested In...

--------------------------------------------------------------------------------

Comments
Add your comments about this article below. You can add comments as a registered user or anonymously. If you choose to post anonymously your comments will be sent to our moderator for approval before they appear on this page. If you choose to post as a registered user your comments will appear instantly. 

When voicing your views via the comment feature, please respect the Diabetes Health community by refraining from comments that could be considered offensive to other people. Diabetes Health reserves the right to remove comments when necessary to maintain the cordial voice of the diabetes community. 

For your privacy and protection, we ask that you do not include personal details such as address or telephone number in any comments posted. 

Don't have your Diabetes Health Username? Register now and add your comments to all our content. 

Register..
Register your Diabetes Health Username here.

 Your Chosen Username:  Your Email Address:  
      
      Chosen Password:  Confirm Password:  
      
       

Have Your Say...
 Registered User     Anonymous 

 Username: Password: 
         
      Comment: 
        
        
Home | News & Blog | Forums | Digital Edition | TV | Subscribe | Contact Us | Donate | Sitemap
©1991-2009 Diabetes Health 13 
-------------- next part --------------
A non-text attachment was scrubbed...
Name: logo4.gif
Type: image/gif
Size: 4058 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment.gif>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: home.gif
Type: image/gif
Size: 67 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0001.gif>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: lg.php?bannerid=437&campaignid=278&zoneid=196&channel_ids=,	&loc=http%3A%2F%2Fwww.diabeteshealth.com%2Fread%2F2009%2F09%2F03%2F6347%2Fmisinformed-immune-system-may-cause-type-i-diabetes%2F%3FisComment%3D1&cb=263ec1a4c3
Type: application/octet-stream
Size: 43 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment.obj>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: lg.php?bannerid=382&campaignid=266&zoneid=197&channel_ids=,	&loc=http%3A%2F%2Fwww.diabeteshealth.com%2Fread%2F2009%2F09%2F03%2F6347%2Fmisinformed-immune-system-may-cause-type-i-diabetes%2F%3FisComment%3D1&cb=2424ff25c9
Type: application/octet-stream
Size: 43 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0001.obj>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: advertisement.png
Type: image/png
Size: 398 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment.png>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: ai.php?filename=dh_support.gif&contenttype=gif
Type: application/octet-stream
Size: 103198 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0002.obj>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: lg.php?bannerid=267&campaignid=244&zoneid=191&channel_ids=,	&loc=http%3A%2F%2Fwww.diabeteshealth.com%2Fread%2F2009%2F09%2F03%2F6347%2Fmisinformed-immune-system-may-cause-type-i-diabetes%2F%3FisComment%3D1&cb=acef231f83
Type: application/octet-stream
Size: 43 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0003.obj>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: forum-button.png
Type: image/png
Size: 3377 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0001.png>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: 0908.jpg
Type: image/jpeg
Size: 11129 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: click-to-subscribe.png
Type: image/png
Size: 5459 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0002.png>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: 0908.jpg
Type: image/jpeg
Size: 10301 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0001.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: see-toc.png
Type: image/png
Size: 3108 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0003.png>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: learn-about-pro-subscription.png
Type: image/png
Size: 3245 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0004.png>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: newsletter-small.gif
Type: image/gif
Size: 11801 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0002.gif>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: see-example-newsletter.png
Type: image/png
Size: 2978 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0005.png>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: lg.php?bannerid=262&campaignid=235&zoneid=192&channel_ids=,	&loc=http%3A%2F%2Fwww.diabeteshealth.com%2Fread%2F2009%2F09%2F03%2F6347%2Fmisinformed-immune-system-may-cause-type-i-diabetes%2F%3FisComment%3D1&cb=379b08c479
Type: application/octet-stream
Size: 43 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0004.obj>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: lg.php?bannerid=438&campaignid=278&zoneid=193&channel_ids=,	&loc=http%3A%2F%2Fwww.diabeteshealth.com%2Fread%2F2009%2F09%2F03%2F6347%2Fmisinformed-immune-system-may-cause-type-i-diabetes%2F%3FisComment%3D1&cb=9eaa808c1d
Type: application/octet-stream
Size: 43 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0005.obj>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: 6347.jpg
Type: image/jpeg
Size: 10523 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0002.jpg>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: 26981
Type: application/octet-stream
Size: 115 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0006.obj>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: myspace_logo_16.gif
Type: image/gif
Size: 910 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0003.gif>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: 16x16-digg-guy.gif
Type: image/gif
Size: 256 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0004.gif>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: donate.png
Type: image/png
Size: 3082 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0006.png>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: body-background.gif
Type: image/gif
Size: 53 bytes
Desc: not available
URL: <http://nfbnet.org/pipermail/diabetes-talk_nfbnet.org/attachments/20090904/1f8f55af/attachment-0005.gif>

More information about the Diabetes-Talk mailing list