[Diabetes-talk] FW: [HAESRD] Fwd: [wmdpg] DPP 10 yr economic data - reported at American Diabetes Assoc Tues 6/28

Sat Jul 16 04:01:02 UTC 2011

Below is the description of the aforementioned study and a link to the press
release about it.

Mike Freeman, President

Diabetes Action Network

National Federation of the Blind

From: Alice Baker [mailto:alicelbaker at gmail.com] 
Sent: Sunday, July 03, 2011 6:05 PM
To: Mike Freeman
Subject: Fwd: [HAESRD] Fwd: [wmdpg] DPP 10 yr economic data - reported at
American Diabetes Assoc Tues 6/28

Hi Mike, 

I am forwarding this to possibly include with references...this is hot of
the press in research and shows marked improvement in Diabetes without
significant weight loss.

Exciting research...ab

-- 
JOYFUL NUTRITION
Empowering you towards nourishing balance...
ALICE BAKER RD LDN
NUTRITION THERAPIST
1345 Clay Street
Winter Park, FL 32789
407-340-8251
www.joyfulnutrition.net
AliceLBaker at gmail.com

This is the study where participants in the lifestyle intervention lost an
average of 1.1kg at the end of 10 years so obviously weight loss was not the
factor that reduced risk of type 2 diabetes.  It was improvements in diet
and exercise, which is what we advocate in HAES!

All - 
I'm sharing the press release from American Diabetes Assoc. This was from a
late breaking oral presentation on Tues 6/28. It is the economic analysis of
the DPP and DPP Outcomes System over 10 years. It's good news for lifestyle
intervention. Here's the link to the release:
http://www.diabetes.org/for-media/2011/DPP-follow-up-Sci-Sessions-2011.html.
I have heard that this data is on its way to publication in a prestigious
journal. Very exciting! 

Efforts to prevent type 2 diabetes in persons at high risk for developing it
improve quality of life and may save money, according to data presented by
researchers at the American Diabetes Association
<http://www.diabetes.org/?&utm_source=WWW&utm_medium=pressrelease&utm_campai
gn=SS> 's 71st Scientific SessionsR.

The 10-year cost-effectiveness analysis, a follow-up to the landmark
National Institutes of Health-sponsored Diabetes Prevention Program (DPP),
found that treatment with metformin or a lifestyle intervention reduced the
costs of medical care by $1700 and $2600 per person, respectively, over 10
years compared to placebo. The cost reductions included lower costs for
inpatient and outpatient care and prescriptions. The study found that the
lifestyle intervention arm cost more to administer than metformin or
placebo. When the reductions in the costs of medical care were balanced
against the costs of the interventions, metformin saved $30 while the
lifestyle intervention cost $1500 per person over the entire 10 years.  The
lifestyle intervention, which aimed for a 7 percent loss in body weight and
150 minutes per week of moderate intensity activity, cut the rates of
progression to diabetes nearly twice as often as treatment with metformin.
The lifestyle intervention also resulted in greater improvement in quality
of life than either metformin or placebo.  Pairing the costs of care with
measures of health and quality of life, both interventions were found to be
highly cost-effective.  

The findings, reported by William H. Herman, MD, MPH, Professor of Medicine
and Epidemiology at the University of Michigan and co-investigator of the
DPP Research Group, are particularly significant because it is so rare for a
health intervention to simultaneously improve health and save money."This
puts diabetes prevention in the category of prenatal care or pediatric
immunizations," said Herman. "It's dramatic when an intervention can improve
the health of the population and potentially save money at the same time."

In the DPP, overweight and obese participants with impaired glucose
tolerance were randomly assigned to lifestyle intervention, metformin or
placebo groups. Initial results reported in 2002 showed that lifestyle
intervention led to a 58% reduction in the development of diabetes, from
about 11% per year to about 5% per year. Metformin resulted in a 31%
reduction in diabetes development. During the next seven-year follow-up
period, when all participants were offered a less intensive lifestyle
intervention and metformin-treated patients were encouraged to continue the
medication, the effectiveness of both treatments was somewhat diminished,
with 34% and 18% reductions in diabetes development over the entire ten
years with lifestyle intervention and metformin, respectively. "The DPP has
shown that lifestyle intervention and metformin can decrease the epidemic of
diabetes that is currently affecting the U.S. and much of the world and, in
doing so, may save money," noted David M. Nathan, MD, the DPP Chairman and a
Professor of Medicine at Harvard Medical School. "The cost-savings may seem
modest now, but any decrease in medical costs is welcome and the savings may
very well increase in the future."  The DPP investigators concluded that
health care and societal policies should support the use of lifestyle
intervention and metformin to prevent or delay diabetes. 

"Currently, there are 79 million people in the U.S. living with prediabetes
who could greatly benefit from policies that help prevent diabetes among
those at high risk," said Griffin P. Rodgers, MD, Director of the National
Institute of Diabetes and Digestive and Kidney Diseases, part of the
National Institutes of Health and the major sponsor of the DPP. "The
investment in clinical research studies, such as the DPP, can pay tremendous
dividends in terms of greater public health and long-term cost savings from
reduced medical costs. Translating these findings into practice will reduce
the development of type 2 diabetes, which has become one of the most common
and costly diseases in the U.S. and around the world."

For more info from the ADbA meeting I point you to: 
http://www.diabetes.org/for-media/?utm_source=WWW
<http://www.diabetes.org/for-media/?utm_source=WWW&utm_medium=ContentPage&ut
m_content=press-releases&utm_campaign=SS>
&utm_medium=ContentPage&utm_content=press-releases&utm_campaign=SS (link to
press releases)

http://professional.diabetes.org/Congress_Display.aspx?TYP=9
<http://professional.diabetes.org/Congress_Display.aspx?TYP=9&SID=501&CID=82
452> &SID=501&CID=82452 (link to video highlights)

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