[stylist] using opposite gender for main characters

[vejas]

Hi,
As all of you know I'm a boy.  However, I often like to use girls 
for my main characters.
Is this wrong? I guess it might not be, but I still think people 
might feel it weird.  For some reason, I like to use girls as my 
main character, and I'm thinking of a story in which the main 
character is a girl.
Any thoughts?
Vejas